FLINN SCIENTIFIC INC. "Your Safer Source for Science Supplies" MSDS #: 835.00 Revision Date: April 2, 2001 Material Safety Data Sheet (MSDS) Section 1 — Chemical Product and Company Identification Tris-(Hydroxymethyl) Aminomethane Flinn Scientific, Inc. P.O. Box 219 Batavia, IL 60510 (800) 452-1261 CHEMTREC Emergency Phone Number: (800) 424-9300 Section 2 — Composition, Information on Ingredients Tris-(hydroxymethyl) Aminomethane Synonym: THAM, 2-amino-2-(hydroxymethyl)-1,3-propanediol CAS#: 77-86-1 Section 3 — Hazards Identification White crystalline solid. Odorless. FLINN AT-A-GLANCE Body tissue irritant. Avoid all body tissue contact. Health-0 Flammability-0 Reactivity-1 Exposure-1 Storage-1 0 is low hazard, 3 is high hazard Section 4 — First Aid Measures Call a physician, seek medical attention for further treatment, observation and support after first aid. Inhalation: Remove to fresh air at once. If breathing has stopped give artificial respiration immediately. Eye: Immediately flush with fresh water for 15 minutes. External: Wash continuously with fresh water for 15 minutes. Internal: Give large quantities of water. Call a physician or poison control at once. Section 5 — Fire Fighting Measures Combustible liquid. NFPA CODE When heated to decomposition, emits toxic fumes of NOx. None established Fire Fighting Instructions: Use triclass, dry chemical fire extinguisher. Firefighters should wear PPE and SCBA with full facepiece operated in positive pressure mode. Section 6 — Accidental Release Measures Restrict unprotected personnel from area. Remove all ignition sources and water. Sweep up, place in sealed bag or container and dispose. Ventilate area and wash spill site after material pickup is complete. See Sections 8 and 13 for further information. Section 7 — Handling and Storage Flinn Suggested Chemical Storage Pattern: Organic #2. Store with alcohols, glycols, amines and amides. Store in a cool, dry place. Deliquescent, store in a Flinn Chem-Saf bag. Section 8 — Exposure Controls , Personal Protection Avoid contact with eyes, skin and clothing. Wear chemical splash goggles, chemical-resistant gloves and chemical-resistant apron. © 2002 Flinn Scientific, Inc. All Rights Reserved. PAGE 1 OF 2 FLINN SCIENTIFIC INC. Tris-(Hydroxymethyl) Aminomethane "Your Safer Source for Science Supplies" MSDS #: 835.00 Material Safety Data Sheet (MSDS) Revision Date: April 2, 2001 Section 9 — Physical and Chemical Properties White crystalline solid. Odorless. Melting Point: 171-172 C Solubility: Water. Freely soluble in alcohol. Boiling Point: 219-220 C @ 10 mm Formula: (CH2OH)3CNH2 Formula Weight: 121.14 Section 10 — Stability and Reactivity Avoid contact with bases and oxidizers. Shelf Life: Poor, hygroscopic. Section 11 — Toxicological Information Acute effects: Irritant. ORL-RAT LD50: 5900 mg/kg Chronic effects: N.A. IHL-RAT LC50: N.A. Target organs: N.A. SKN-RBT LD50: N.A. N.A. = Not available, not all health aspects of this substance have been fully investigated. Section 12 — Ecological Information Data not yet available. Section 13 — Disposal Considerations Please consult with state and local regulations. Flinn Suggested Disposal Method #26a is one option. Section 14 — Transport Information Shipping Name: Not regulated Hazard Class: N/A UN Number: N/A N/A = Not applicable Section 15 — Regulatory Information TSCA-listed, EINECS-listed (201-064-4). Section 16 — Other Information Consult your copy of the Flinn Scientific Catalog/Reference Manual for additional information about laboratory chemicals. This Material Safety Data Sheet (MSDS) is for guidance and is based upon information and tests believed to be reliable. Flinn Scientific Inc. makes no guarantee of the accuracy or completeness of the data and shall not be liable for any damages relating thereto. The data is offered solely for your consideration, investigation, and verification. Flinn Scientific Inc. assumes no legal responsibility for use or reliance upon this data. FLINN SCIENTIFIC INC. "Your Safer Source for Science Supplies" Need a Chemical Fast? - Order from Flinn flinn@flinnsci.com www.flinnsci.com P.O. Box 219 Batavia IL 60510 (800) 452-1261 Fax (866) 452-1436 PAGE 2 OF 2 © 2002 Flinn Scientific, Inc. All Rights Reserved.